Snow has appeared in various films, including The Pacifier (2005), John Tucker Must Die (2006), Hairspray (2007), Prom Night (2008), Would You Rather (2012), the Pitch Perfect film series (2012–2017), Bushwick (2017), Hangman (2017), Someone Great (2019), and X (2022). She also appeared in the NBC legal comedy-drama series Harry's Law (2011) and in the Fox drama series Almost Family (2019–2020).
Snow is the co-founder of the Love Is Louder movement, a project by the not-for-profit Jed Foundation, dedicated to stop bullying in schools. Snow also started a mental health letter writing initiative in 2020 called"September Letters".